Not sure how close what I'm running is to what you're looking for -- what are you looking for in Eclipse Phase? The game I am running is closer to Transhuman Space (and will be using modified GURPS rules) than Eclipse Phase. If you're looking for a setting in which you can play a mind that hops easily between different bodies in a transhumanist future, my game might interest you. If you're looking for more of the horror aspect (destroyed Earth, Things Man Was Not Meant to Know, etc, etc), my game probably won't be quite where you want to be. The theme of the game is a future where the various political, religious, and philosophical differences that rend through society today. Here are a few examples: Faith vs. Understanding: The US has divided along partisan lines, and part of that division comes down to the argument between science and religion. Faith -- the idea that no matter what evidence is presented to the contrary, things are the way you believe them to be, expressed in the comment by the nameless Bush adviser who stated that while us 'reality-based' people examined the facts, they'd make their own reality. It's opposite: Understanding. The idea that the universe has always behaved and always will behave a given way, regardless of mankind's desires, and that the way to exist in the universe is to understand the laws that govern us. Faith isn't quite as irrational as it may seem, given a hidden manaclysm that allows those with the strongest of wills and the weakest of attachment to the Scientific Method the ability to literally shape reality to their whims. With this, those men of Faith can still continue the argument, with force of arms more often than not, even as their scientific knowledge and understanding slips. Liberal vs. Conservative: As mentioned above, the US split on ideological lines. Conservatives, angry about their perceptions of how Liberals treated them, fled to friendlier grounds, mostly heading South and East into the lands of the old Confederacy, where they could be free of those damn immoral Liberals. Liberals, especially honest-to-goodness Communists, fled North and towards the coasts, establishing Liberal utopias, free of those damn backwards Conservatives. Then they started drawing lines in the sand, and given that they'd segregated themselves along ideological lines, they rapidly lost any and all desire to work with the other side. The end result? Several decades worth of war, interspaced with more peaceful times, but still with the drumbeat in the background. Technology vs. Magic: Related to the first, the science-believing Northern fragment of the USA, still calling itself as such, developed advanced technologies, such as cyberswarms, cyber- and bio-shells, artificial intelligence, artificial life forms, and other advanced technologies. Their Southern counterparts, calling themselves the Christian States of America (with an unfortunate acronym the USA quickly seized on to make fun of), eschewed advanced technology, and reverted mostly to 1950s era technology, without the 'space-age' feel that characterized the real 1950s. Similar to the Preservationist (do not alter nature, including our own bodies) vs. Transhumanist (become more than human, as Evolution intended) debate in THS. Concepts that work in this setting include: Cyborg warriors -- not as common as in other settings, but not impossible. Shell operators -- Why become a cyborg when you can just jack into one. Best body for the job. Even biosophants can do this, thanks to interface implants. Biological Weapons - Most bioroids are built cheaply and mass-produced, but perhaps someone decided they wanted to build Khan from Star Trek, and took whatever shortcuts they needed to... Artificial Intelligences - Intelligent life no longer is restricted to bags of mostly water with some protein scattered around. Renegade Angel - (Already got one, won't want more than 1 or 2) Not all of the signature enforcers of the Christian States of America remain loyal...or corrupted. Some see through the lies and the corruption of the all-powerful Southern Baptist Church, and can't reconcile the words of Jesus with the actions of the corrupted church leaders. They then flee, and become some of the strongest freedom fighters for liberating the oppressed citizens of the South -- that is, if they can survive the judgmental attitudes of Northerners who are supposedly above prejudice. If the idea looks interesting, private message me with some ideas about what you want to play, or any questions you might have. I'll do my best to answer them.