When uploading pictures or pdf images into a handout, the upload bar sits and sits. I see it appear in the handouts section of the character/handouts window and I wait. Finally I just click "save changes" and when I check, it is fine. Same with remove option - after a bit I see it removed from the handout in the character/handouts window, but it never is removed from the handout. If I then "save changes" and reopen it, it is then gone.
