Not with a chat text or macro command (unless you use API), but using the FX Tool you can point and click any place on a page including not-on-tokens, Wiki docs for this, <a href="https://wiki.roll20.net/Toolbox_Overview" rel="nofollow">https://wiki.roll20.net/Toolbox_Overview</a> As Brian mentioned you can use Selected token for some of the FX, the ones like Burn or Glow or Nova that don't require a Target if there is a Selected. (Compare with FX like Beam or Missile that needs both origin and target, thus makes you use the Target clicking feature). Wiki docs for Selected, <a href="https://wiki.roll20.net/Macros#Using_a_Selected_To" rel="nofollow">https://wiki.roll20.net/Macros#Using_a_Selected_To</a>...