I have played extensively in the DnD d20 universe, 3.0 and 3.5. I tried a 4.0 game, and thought it was really terrible comparatively. I would really enjoy playing a Nightbane campaign, since I have little experience in it, and it looks incredible. The biggest hold up is that I don't know enough about the setting to feel comfortable running a group through it, and throughout every inch of this site, I could not find one single mention of a Nightbane game being run. Of course we'd have to find a few players too, but considering the rarity of the setting on this site and the lacking mention of it on the site or on the forums, I'm guessing finding a GM experienced with the setting would be even more difficult, so I'm starting on that first. :p
<a href="http://en.wikipedia.org/wiki/Nightbane" rel="nofollow">http://en.wikipedia.org/wiki/Nightbane</a>
E: Also, this campaign from what I've seen and understand is very dark, very macabre, and (frequently) very NSFW. Especially if you're starting the campaign anywhere close to Dark Day, when all hell broke loose.