It would technically be possible to do with an API script that would maintain a separate state of your handout and allow an "edit" and "view" mode to be toggled on it, or possibly to have a rendered version of a handout where formulas were applied. It would be a bit of a daunting task to accomplish and I'm not sure how much payoff would be there. Probably easier to just have a google doc and keep the link in the GM notes for easy update/copy.