If you give us more info we're more likely to be able to diagnose the problem.    Can you start by providing a screenshot of how the game looks like when the map have disappeared?  How well do you know Roll20 and its features? Is it possible you switched to  another (map) page ?  Is it possible you mistakenly deleted the map when you where manipulating objects in the module?  Do you remember exactly what you did before it disappeared, and what  layer you had active ?  (In case you approve a Roll20 dev taking a look at the game that have the problem, could you mention the exact name of the campaign this is happening in?)