Do you go for the realistic, hard-to-do style that is reminiscent of  Balder's Gate ?  Or do you go for the more cartoony style that people like  Devin Night  create?
 
 
 Personally I go for the uber realistic style.  It just looks better.  But this has ended up demanding a lot of work from me but I think the quality of the maps I have made are  well  worth it!