Yes, this is possible, in fact, I just answered this same question yesterday. :D I am assuming the D&D 5e by Roll20 sheet. Let me know if you are using something else. Put he NPC in edit mode (click the upper right gear icon). Near the bottom you will find a check box. Check to make sure the monster is set up to be a spell casting npc. For instance, if I drag a spell onto a lich, the spell is added. If I drag it onto a goblin, the spell is technically added, but won't display. So click the option to make it into a spell caster: Before: After: Dreaded Goblin-With-A-Magic-Missile: