I like mostly home brewed not lore friendly games because then you are mostly not limited to what you can do. for example in a home brewed warhammer 40k game you can have the Ultramarine's have corruption withing there ranks and your char can be an outcast that is a psychic null (someone who isn't affected by the warp) and that was excommunicated because he called out the corruption and a lot of other crazy stuff.
i'm willing to learn and play traditional games as long as it doesn't require you to have your own rule book