Hi Aaron. Sure, good question, others will come along with more tips. It has been done. You could get some relevant tips from previous threads that were about using Roll20 in-person. Many people send Roll20 to a TV for larger viewing by a group. If everyone shares one wireless mouse to control the Player's side, then a tip is for the GM to set every character's token as able to be controlled by all players. Again, there are many ways, so you have options, but one possible set-up is: Have the game running with just 2 accounts logged in, the GM on their end, and all the Players sharing one account ("The Players"). If you do video, this will have the GM casting his face in one video box, and all the players sitting around the table looking very small in the other video box. Or you can have the GM's video turned on, and disable the Player-side video, just showing a picture in the video box instead. Probably one of the biggest issues to resolve in your set-up would be audio, making it so that everyone can hear your GM over open-air speakers in the room, yet also so the Players can speak back to the DM (a mic that can pick up everyone, or a separate mic for each person) and having the Mics NOT pick up the sound of the speakers which would cause a feedback loop. There are many techniques to address this, depending on your gear, your room, and whether you want to use Roll20 voice or an external voice program like Discord or Skype.