As far as I can tell people are playing both rather regularly on roll20, so I suggest just go with what you like better. When you get into roleplaying the system is for how you think and interact with the world you're in, so if you don't like the system much, it's harder to have fun, and I know as I have been in a group that regularly likes to experiment with different systems. Some are very cool and interesting, but not really my style so it was hard to get into the game as much, although combining a good system with bad storytelling amounts to the same thing. 4e rules IMO have a very combat oriented system where every character is required to take a series of special abilities that are effective in combat and can optionally take abilities that are effective out of combat - and pretty much anyone is able to take the Ritual skill to do ritual spells as long as you have the material costs. Pathfinder has various classes and options - many of which allow one class to touch at another class without the need to multi-class - although some things still require multi-classing. There are many ways to build a character and building a character to be good at skills and roleplaying, and weak at fighting is possible. Don't get blinded by world settings. Pathfinder may have a very in depth world setting created by Paizo, but it's not like everyone uses it, or if they do, are experts on it. Many people much prefer to make homebrew campaigns so focus on a system of RULES and not stories when choosing what you want to play. Seriously, you could adapt Pathfinders world setting into 4e if you really wanted to. Or take it back to AD&D or Classic. Stories can be changed to adapt to systems, but it's harder to adapt a system to a story.
